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Key Documents

RAB0312

Sigma-Aldrich

Rat Interleukin-6 ELISA Kit

for for cell lysate and tissue lysate

Synonyme(s) :

IL-6, Interleukin-6 

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About This Item

Code UNSPSC :
41116158
Nomenclature NACRES :
NA.32

Espèces réactives

rat

Conditionnement

kit of 96 wells (12 strips x 8 wells)

Technique(s)

ELISA: suitable
capture ELISA: suitable

Entrée

sample type tissue lysate
sample type cell lysate

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 15 pg/mL
standard curve range: 40.96-10000 pg/mL

Méthode de détection

colorimetric

Conditions d'expédition

wet ice

Température de stockage

−20°C

Informations sur le gène

rat ... Il6(24498)

Catégories apparentées

Description générale

The Rat IL-6 ELSA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Rat IL-6 cell lysate and tissue lysate.

Immunogène

Recombinant Rat IL-6

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Rat Interleukin-6 ELISA Kit has been used to determine the plasma level of interleukin-6 (IL-6) via ELISA.

Actions biochimiques/physiologiques

Interleukin-6 (IL-6) acts as a neuromodulation factor. IL-6 has two signalling pathways, known as classic signalling pathway and trans-signalling pathway. It has a neuroprotective role in ischemic stroke, by activating IL-6/interleukin 6 receptor (IL-6R)/signal transducers and activators of transcription 3 (STAT3) signalling pathway. IL-6 is a multifunctional cytokine, which is implicated in acute inflammation. IL-6 is associated with SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome.

Autres remarques

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Composants de kit également disponibles séparément

Réf. du produit
Description
FDS
  • RABDIL6ELISA 5X Sample Diluent Buffer (Item D2)FDS
  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)FDS
  • RABLYSIS12X Cell Lysis Buffer (Item J)FDS
  • RABSTOP3ELISA Stop Solution (Item I)FDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)FDS
  • RABWASH420X Wash Buffer (Item B)FDS

Pictogrammes

Corrosion
GHS05

Mention d'avertissement

Warning

Mentions de danger

H290

Conseils de prudence

P234 - P390

Classification des risques

Met. Corr. 1

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Interleukin-6 RNA knockdown ameliorates acute lung injury induced by intestinal ischemia reperfusion in rats by upregulating interleukin-10 expression
Yuan B, et al.
Molecular Medicine Reports, 16(3), 2529-2537 (2017)
AT1 receptor blocker losartan protects against mechanical ventilation-induced diaphragmatic dysfunction
Kwon OS, et al.
Journal of Applied Physiology, 119(10), 1033-1041 (2015)
Effects of interleukin-6 and IL-6/AMPK signaling pathway on mitochondrial biogenesis and astrocytes viability under experimental septic condition
Chen XL, et al.
International Immunopharmacology, 59, 287-294 (2018)
Lars Wallentin et al.
European heart journal, 41(41), 4037-4046 (2020-09-29)
The global COVID-19 pandemic is caused by the SARS-CoV-2 virus entering human cells using angiotensin-converting enzyme 2 (ACE2) as a cell surface receptor. ACE2 is shed to the circulation, and a higher plasma level of soluble ACE2 (sACE2) might reflect
Serum IL-6 and IL-23 levels and their correlation with angiogenic cytokines and disease activity in ankylosing spondylitis, psoriatic arthritis, and SAPHO syndrome
Przepiera-Bkedzak H, et al.
Mediators of Inflammation, 2015, 2529-2537 (2015)
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