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Key Documents

P6775

Sigma-Aldrich

Palmitoleoyl coenzyme A lithium salt

~90%

Synonyme(s) :

cis-9-Hexadecenoyl Coenzyme A

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About This Item

Formule empirique (notation de Hill):
C37H64N7O17P3S
Numéro CAS:
18198-76-0
Poids moléculaire :
1003.93
Numéro MDL:
MFCD00079261
Code UNSPSC :
41106305
ID de substance PubChem :
24898796
Nomenclature NACRES :
NA.51

Pureté

~90%

Niveau de qualité

200

Forme

powder

Température de stockage

−20°C

Chaîne SMILES 

([Li].C(CCCCCCC\C=C/CCCCCC)(=O)SCCNC(CCNC([C@@H](C(COP(OP(OC[C@@H]1[C@H]([C@H]([C@@H](O1)N1C=NC=2C(N)=NC=NC12)O)OP(=O)(O)O)(=O)O)(=O)O)(C)C)O)=O)=O)

InChI

1S/C37H64N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-28(46)65-21-20-39-27(45)18-19-40-35(49)32(48)37(2,3)23-58-64(55,56)61-63(53,54)57-22-26-31(60-62(50,51)52)30(47)36(59-26)44-25-43-29-33(38)41-24-42-34(29)44/h9-10,24-26,30-32,36,47-48H,4-8,11-23H2,1-3H3,(H,39,45)(H,40,49)(H,53,54)(H,55,56)(H2,38,41,42)(H2,50,51,52)/b10-9+

Clé InChI

QBYOCCWNZAOZTL-MDZDMXLPSA-N

Application

Coenzyme A functions as an acyl group carrier, acetyl-CoA. Palmitoleoyl coenzyme A (Palmitoleoyl-CoA) may be used in comparative long chain fatty acyl-CoA studies such as the effects of long-chain acyl-coenzyme A esters on cardiac K(ATP) channels and lipotoxic footprinting.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Makoto Miyazaki et al.
Prostaglandins, leukotrienes, and essential fatty acids, 68(2), 113-121 (2003-01-23)
Stearoyl-CoA desaturase (SCD) (EC 1.14.99.5) is an endoplasmic reticulum-bound enzyme that catalyzes the delta9-cis desaturation of saturated fatty acyl-CoAs, the preferred substrates being palmitoyl- and stearoyl-CoA, which are converted to palmitoleoyl- and oleoyl-CoA, respectively. These monounsaturated fatty acids are used
Romain Harmancey et al.
Journal of lipid research, 51(6), 1380-1393 (2010-01-23)
The "lipotoxic footprint" of cardiac maladaptation in diet-induced obesity is poorly defined. We investigated how manipulation of dietary lipid and carbohydrate influenced potential lipotoxic species in the failing heart. In Wistar rats, contractile dysfunction develops at 48 weeks on a
Andrea J Lengi et al.
Lipids, 42(6), 499-508 (2007-05-01)
Stearoyl-CoA desaturase (SCD) is an enzyme responsible for the production of cis-9, trans-11 conjugated linoleic acid in ruminant fats, and for the synthesis of palmitoleoyl-CoA and oleoyl-CoA. To date, only one SCD isoform has been described in ruminant species, although
G X Liu et al.
Circulation research, 88(9), 918-924 (2001-05-23)
ATP-sensitive K (K(ATP)) channels are inhibited by cytosolic ATP, a defining property that implicitly links these channels to cellular metabolism. Here we report a direct link between fatty acid metabolism and K(ATP) channels in cardiac muscle cells. Long-chain (LC) acyl-coenzyme
Dirk Schulze et al.
The Journal of physiology, 552(Pt 2), 357-367 (2003-10-17)
Phosphatidylinositol phosphates (PIPs, e.g. PIP2) and long-chain acyl-CoA esters (e.g. oleoyl-CoA) are potent activators of KATP channels that are thought to link KATP channel activity to the cellular metabolism of PIPs and fatty acids. Here we show that the two
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