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L3262

Sigma-Aldrich

Anti-Lactoferrin antibody produced in rabbit

fractionated antiserum, lyophilized powder

Synonyme(s) :

Anti-Draculin, Anti-Draculin-1

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About This Item

Numéro MDL:
MFCD00162524
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

rabbit

Niveau de qualité

200

Conjugué

unconjugated

Forme d'anticorps

fractionated antiserum

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

lyophilized powder

Espèces réactives

human

Conditionnement

vial of 2 mL lyophilized antiserum

Technique(s)

direct ELISA: 1:10,000 using using human lactoferrin

Numéro d'accès UniProt

P02788

Température de stockage

2-8°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... LTF(4057)

Description générale

Lactoferrin, globular glycoprotein belongs to transferrin protein family. It is mapped to human chromosome 3p21.31. Lactoferrin comprises 692 amino acids with two globular lobes linked by α-helix and belongs to transferrin family. It exists in three isoforms namely lactoferrin-α, lactoferrin-γ, and lactoferrin-β. Lactoferrin corresponds to a molecular weight of 80 kDa.

Spécificité

Rabbit polyclonal anti-lactoferrin antibody reacts with purified lactoferrin and human milk, but does not react with human serum proteins.

Application

Anti-Lactoferrin antibody produced in rabbit has been used in:
  • western blotting
  • indirect immunofluorescence
  • flow cytometry
  • enzyme-linked immunosorbent assay (ELISA)

Actions biochimiques/physiologiques

A primary function of lactoferrin is to bind and transport iron ions. However, lactoferrin is also an effective antibacterial, antiviral, antiparasitic, catalytic (RNA degrading), anti-cancer molecule. It elicits anti-inflammatory effects in asthma. It has immunomodulatory and anti-inflammatory functionality and is a potential protein nutraceutical.

Forme physique

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2

Reconstitution

Reconstitute with 2 ml deionized water.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Expression, purification, and breast cancer cell inhibiting effect of recombinant human lactoferrin C-lobe
Hu L, et al.
Bioscience, Biotechnology, and Biochemistry, 80(2), 257-263 (2016)
Alan Grupioni Lourenço et al.
World journal of virology, 3(2), 11-17 (2014-07-16)
To study the effect of seminal plasma on Chemokine (C-C motif) ligand 20 (CCL20) production by epithelial cells and its relationship with lactoferrin. HEC-1A cells, a cell line derived from a monostratified endocervical epithelium, were incubated with samples of seminal
Lulu Hu et al.
Scientific reports, 7(1), 4230-4230 (2017-06-28)
Lactoferrin (LTF), an important first line defense molecule against infection, is a common target for humoral autoimmune reactions in humans. Since LTF is a multifunctional protein capable of activating innate immune cells via various surface receptors, we hypothesized that LTF-containing
Genetic and epigenetic inactivation of LTF gene at 3p21. 3 in lung cancers
Iijima H, et al.
International Journal of Cancer. Journal International Du Cancer, 118(4), 797-801 (2006)
Neutrophil extracellular traps contain selected antigens of anti-neutrophil cytoplasmic antibodies
Panda R, et al.
Frontiers in Immunology, 8(2), 439-439 (2017)
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