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Key Documents

332R-1

Sigma-Aldrich

Somatostatin (EP130) Rabbit Monoclonal Primary Antibody

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100
500

Conjugué

unconjugated

Forme d'anticorps

culture supernatant

Type de produit anticorps

primary antibodies

Clone

EP130, monoclonal

Description

(For In Vitro Diagnostic Use in Select Regions (See Chart))

Forme

buffered aqueous solution

Espèces réactives

human

Conditionnement

bottle of 1.0 mL predilute (332R-17)
bottle of 7.0 mL predilute (332R-18)
vial of 0.1 mL concentrate (332R-14)
vial of 0.5 mL concentrate (332R-15)
vial of 1.0 mL concentrate (332R-16)

Fabricant/nom de marque

Cell Marque™

Technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Isotype

IgG

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Informations sur le gène

human ... SST(6750)

Description générale

Somatostatin is a peptide hormone widely distributed throughout the body and is an important regulator of endocrine and nervous system function. Somatostatin can also be found in gastrointestinal and bronchopulmonary endocrine cells, thymic endocrine cells, and thyroid C-cells. Anti-somatostatin is a useful marker of D-cells of pancreatic islet cells.1,2 D-cells identification can be used to identify hyperplasia of the pancreatic islets of Langerhans and tumors arising from these cells. Anti-somatostatin recognizes somatostatin-containing cells in pancreatic tumors, islet cell hyperplasia, and islet cells originating in pancreatic ductules.3-7

Qualité


IVD
IVD
IVD
RUO

Liaison

Somatostatin Positive Control Slides, Product No. 332S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Notes préparatoires

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Maria Angelova Tzaneva
Acta histochemica, 105(2), 191-201 (2003-07-02)
Five types of endocrine cells are found in the human antral gastric mucosa: gastrin (G) cells, somatostatin (D) cells, enterochromaffin (EC) cells and cells with an unknown secretory product (D1 cells and P cells). The content of secretory granules, gastrin
P Kanavaros et al.
Histology and histopathology, 5(3), 325-328 (1990-07-01)
Serotonin-producing pancreatic endocrine tumours are rare neoplasms which in most cases exhibit malignant biological behaviour. These tumours, in the majority of the well-documented cases, are composed of argyrophil- and argentaffin-positive cells which contain large pleomorphic neurosecretory granules. In contrast, argyrophilic
G J Krejs et al.
The New England journal of medicine, 301(6), 285-292 (1979-08-09)
Diabetes mellitus, steatorrhea, cholelithiasis and a tumor distorting the duodenum prompted a work-up for somatostatinoma in a 52-year-old man. The responses of pancreatic B-cells but not of A-cells to nutrient stimuli were inhibited, and growth-hormone release was suppressed, suggesting somatostatin
G Chejfec et al.
Ultrastructural pathology, 16(5), 537-545 (1992-09-01)
Upper gastrointestinal tract neuroendocrine tumors producing predominantly somatostatin have thus far been described only in the duodenum; their characteristic features include the frequent presence of psammoma bodies (psammomatous somatostinomas), and the association with von Recklinghausen's neurofibromatosis. Gastric neuroendocrine tumors, on

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