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Key Documents

Y0001462

Acetylsulfadiazine

European Pharmacopoeia (EP) Reference Standard

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About This Item

Formule empirique (notation de Hill):
C12H12N4O3S
Numéro CAS:
Poids moléculaire :
292.31
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

sulfadiazine

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

InChI

1S/C12H12N4O3S/c1-9(17)15-10-3-5-11(6-4-10)20(18,19)16-12-13-7-2-8-14-12/h2-8H,1H3,(H,15,17)(H,13,14,16)

Clé InChI

NJIZUWGMNCUKGU-UHFFFAOYSA-N

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Acetylsulfadiazine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

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Lot/Batch Number

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Consulter la Bibliothèque de documents

The case: 69 year old man with sand in the urine. N-acetylsulfadiazine crystals.
A K Schuler et al.
Kidney international, 72(6), 769-770 (2007-09-07)
D Westerlund et al.
Journal of pharmaceutical sciences, 71(10), 1142-1145 (1982-10-01)
Sulfadiazine and N4-acetylsulfadiazine were determined in biological fluids by the direct injection (plasma after protein precipitation and urine after dilution 100 times) of 20 microliters on a silica gel column. The mobile phase was an aqueous citrate buffer (pH 4.0)
T Bergan et al.
Chemotherapy, 32(6), 478-485 (1986-01-01)
The study was aimed at analyzing the pharmacokinetics of sulphadiazine (SDZ) and trimethoprim (TMP) in geriatric patients and was carried out in two stages. The first stage compared 11 geriatric patients (68-89 years old) and 9 healthy volunteers (21-34 years
Sulfadiazine/N4-acetylsulfadiazine crystalluria in a patient with the acquired immune deficiency syndrome (AIDS)
J L Potter et al.
Clinica chimica acta; international journal of clinical chemistry, 230(2), 221-224 (1994-10-31)
G C Batzias et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 769(2), 253-259 (2002-05-09)
A new method for simultaneous quantification of trimethoprim, sulfadiazine and N4-acetylsulfadiazine in plasma of broilers at levels down to 13-16 ng/ml has been developed. Samples were deproteinized with acetonitrile, defatted with hexane, and extracted with dichloromethane. Chromatographic analysis was carried

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