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P3700000

6-Propyl-2-thiouracil

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

6-Propyl-2-thiouracil, 2,3-Dihydro-6-propyl-2-thioxo-4(1H)-pyrimidinone, 4-Hydroxy-2-mercapto-6-propylpyrimidine

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About This Item

Formule empirique (notation de Hill):
C7H10N2OS
Numéro CAS:
51-52-5
Poids moléculaire :
170.23
Numéro Beilstein :
130039
Numéro MDL:
MFCD00006041
Code UNSPSC :
41116107
ID de substance PubChem :
329820187
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Description

enzyme inhibitor

Famille d'API

propylthiouracil

Fabricant/nom de marque

EDQM

Pf

218-220 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

CCCC1=CC(=O)NC(=S)N1

InChI

1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)

Clé InChI

KNAHARQHSZJURB-UHFFFAOYSA-N

Informations sur le gène

human ... DIO1(1733) , TPO(7173)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Propylthiouracil EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

Health hazardExclamation mark
GHS08,GHS07

Mention d'avertissement

Warning

Mentions de danger

H302,H351

Classification des risques

Acute Tox. 4 Oral - Carc. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Alcohol is the most common cause of liver disease in the Western world today. Randomised clinical trials have addressed the question whether propylthiouracil has any efficacy in patients with alcoholic liver disease. The objectives were to assess the efficacy of
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Nature reviews. Nephrology, 8(8), 476-483 (2012-06-06)
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To report the successful management of thyrotoxicosis in a seriously ill 47-year-old man with a perforated gastric ulcer in whom oral intake was contraindicated. Our patient was treated with 400 mg of propylthiouracil (PTU) every 6 hours in the form
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