95054

Azelaic acid

analytical standard

• Synonyme(s) : Nonanedioic acid
• Formule linéaire : HO₂C(CH₂)₇CO₂H
• Numéro CAS: 123-99-9
• Poids moléculaire : 188.22
• Numéro Beilstein : 1101094
• Numéro CE : 204-669-1
• Numéro MDL: MFCD00004432
• Code UNSPSC : 85151701
• ID de substance PubChem : 329770414
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 100
• Densité de vapeur: 6.5 (vs air)
• Pression de vapeur: <1 mmHg ( 20 °C)
• Pureté: ≥98.5% (GC)
• Durée de conservation: limited shelf life, expiry date on the label
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Impuretés: ≤0.5% water
• Point d'ébullition: 286 °C/100 mmHg (lit.)
• Pf: 106-112 °C; 109-111 °C (lit.)
• Application(s): cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care
• Format: neat
• Chaîne SMILES: OC(=O)CCCCCCCC(O)=O
• InChI: 1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)
• Clé InChI: BDJRBEYXGGNYIS-UHFFFAOYSA-N

Description

Description générale

Azelaic acid (heptane-l,7-dicarboxylic acid), a dicarboxylic saturated acid, is an active component of some topical anti-acne preparations. It is reportedly identified in cosmetics and pharmaceuticals. Azelaic acid is found to suppress the growth of Propionibacterium spp. and reduce keratinization.

This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find all available reference materials for compounds listed in 10/2011 here

Application

Azelaic acid may be used as an analytical reference standard for the quantification of the analyte in the following:

• Tobacco using gas chromatography coupled to mass spectrometry (GC-MS).
• Topical preparations using reversed-phase liquid chromatographic (LC) with UV-Vis detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319
• Conseils de prudence: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 410.0 °F - closed cup
• Point d'éclair (°C): 210 °C - closed cup