524394

4α-Phorbol-12,13-didecanoate

>99% (HPLC), solid, PDD and PMA negative control, Calbiochem^®

• Synonyme(s) : 4α-Phorbol-12,13-didecanoate, 4αPDD, PKC Activator I, Negative Control
• Formule empirique (notation de Hill): C₄₀H₆₄O₈
• Numéro CAS: 27536-56-7
• Poids moléculaire : 672.93
• Numéro MDL: MFCD00036737
• Code UNSPSC : 12352211
• Nomenclature NACRES : NA.77

Propriétés

• product name: 4α-Phorbol-12,13-didecanoate, Inactive on mouse skin as an inflammatory and tumor-promoting agent.
• Niveau de qualité: 100
• Pureté: >99% (HPLC)
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze
• Solubilité: DMSO: soluble; ethanol: soluble
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• InChI: 1S/C40H64O8/c1-7-9-11-13-15-17-19-21-32(42)47-36-28(4)39(46)30(24-29(26-41)25-38(45)31(39)23-27(3)35(38)44)34-37(5,6)40(34,36)48-33(43)22-20-18-16-14-12-10-8-2/h23-24,28,30-31,34,36,41,45-46H,7-22,25-26H2,1-6H3/t28-,30+,31-,34-,36-,38+,39-,40-/m1/s1
• Clé InChI: DGOSGFYDFDYMCW-OEFRVDPMSA-N

Description

Description générale

Inactive on mouse skin as an inflammatory and tumor-promoting agent. Useful as a negative control for Phorbol-12,13-didecanoate (PDD; Cat. No. 524392) and Phorbol-12-myristate-13-acetate (PMA; Cat. No. 524400).

Reported to be inactive on mouse skin as an inflammatory and tumor-promoting agent. Used as a negative control for phorbol-12,13-didecanoate (PDD, Cat. No. 524392) and phorbol-12-myristate-13-acetate (PMA, Cat. No. 524400).

Actions biochimiques/physiologiques

Cell permeable: no

Primary Target
A negative control for Phorbol-12,13-didecanoate (PDD) and Phorbol-12-myristate-13-acetate (PMA)

Product does not compete with ATP.

Reversible: no

Conditionnement

Packaged under inert gas

Avertissement

Toxicity: Highly Toxic (H)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 6 months at -20°C.

Autres remarques

Akiguchi, I., et al. 1993. Endocrinology 138, 379.
Clarke, B.L., et al. 1993. Endocrinology132, 1168.
Natarajan, V. and Garcia, J.G. 1993. J. Lab. Clin. Med.121, 337.
Slomiany, B.L., et al. 1992. J. Physiol. Pharmacol.43, 223.

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08,GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H300 + H310 + H330,H314,H317,H334,H351
• Conseils de prudence: P201 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Carc. 2 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable