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1.03893

SAFC

Acide benzènesulfonique

EMPROVE® EXPERT

Fabrication pharma

Synonyme(s) :

Benzene sulphonic acid, Benzenesulphonic acid, Besylic acid, Phenylsulfonic acid, Phenylsulphonic acid

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About This Item

Formule linéaire :
C6H5SO3H
Numéro CAS:
98-11-3
Poids moléculaire :
158.18
Numéro Beilstein :
742513
Numéro CE :
202-638-7
Numéro MDL:
MFCD00011689
Code UNSPSC :
12352005

Source biologique

synthetic

Niveau de qualité

500

Gamme de produits

EMPROVE® EXPERT

Forme

crystalline

Technique(s)

API processing | cocrystal formation: suitable
API processing | salt formation: suitable

Impuretés

endotoxins, low

Application(s)

liquid formulation
parenterals
pharmaceutical

Chaîne SMILES 

OS(=O)(=O)c1ccccc1

InChI

1S/C6H6O3S/c7-10(8,9)6-4-2-1-3-5-6/h1-5H,(H,7,8,9)

Clé InChI

SRSXLGNVWSONIS-UHFFFAOYSA-N

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Catégories apparentées

Description générale

For protein-based therapeutics, such as monoclonal antibodies (mAbs) or plasma derived proteins, often highly concentrated protein formulations are required to meet intended dosing regimens. However, this usually comes with elevated viscosities and presents a challenge in the manufacturing process and final formulation. Our Viscosity Reduction Excipient Platform reduces the viscosity and helps overcome challenges associated with highly concentrated protein solutions.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation.
Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

The Viscosity Reduction Platform is based on the combination of two new excipients, one amino acid component with one anionic component, that together can better reduce protein viscosity beyond levels achieved with single excipients. Also, combining the two components enables a balance of viscosity reduction and protein stabilization. Benzenesulfonic Acid Emprove® Expert is part of this new proprietary technology platform.

Conditionnement

1038930500 / 500g / Glass bottle
1038931000 / 1kg / Glass bottle

Informations légales

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

CorrosionExclamation mark
GHS05,GHS07

Mention d'avertissement

Danger

Mentions de danger

H302,H314

Classification des risques

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Classe de danger pour l'eau (WGK)

WGK 1

Certificats d'analyse (COA)

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Articles

Viscosity Reduction in High Concentration TFF

This overview describes how use of viscosity-reducing excipients can address viscosity challenges in high concentration tangential flow filtration (TFF) and improve process economics.

Viscosity Reduction in High Concentration TFF

This overview describes how use of viscosity-reducing excipients can address viscosity challenges in high concentration tangential flow filtration (TFF) and improve process economics.

Viscosity Reduction in High Concentration TFF

This overview describes how use of viscosity-reducing excipients can address viscosity challenges in high concentration tangential flow filtration (TFF) and improve process economics.

Viscosity Reduction in High Concentration TFF

This overview describes how use of viscosity-reducing excipients can address viscosity challenges in high concentration tangential flow filtration (TFF) and improve process economics.

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