320293

Dimethyl sulfate

≥99%

• Synonyme(s) : Sulfuric acid dimethyl ester
• Formule linéaire : (CH₃O)₂SO₂
• Numéro CAS: 77-78-1
• Poids moléculaire : 126.13
• Numéro Beilstein : 635994
• Numéro CE : 201-058-1
• Numéro MDL: MFCD00008416
• Code UNSPSC : 12352108
• ID de substance PubChem : 24859257
• Nomenclature NACRES : NA.22

Propriétés

• Densité de vapeur: 4.3 (vs air)
• Niveau de qualité: 200
• Pression de vapeur: 0.7 mmHg ( 25 °C)
• Pureté: ≥99%
• Forme: liquid
• Température d'inflammation spontanée: 923 °F
• Indice de réfraction: n20/D 1.386 (lit.)
• Point d'ébullition: 188 °C (lit.)
• Pf: −32 °C (lit.)
• Densité: 1.333 g/mL at 25 °C (lit.)
• Chaîne SMILES: COS(=O)(=O)OC
• InChI: 1S/C2H6O4S/c1-5-7(3,4)6-2/h1-2H3
• Clé InChI: VAYGXNSJCAHWJZ-UHFFFAOYSA-N

Description

Application

Dimethyl sulfate is a powerful methylating reagent for the methylation of carboxylic acids, alcohols, phenols, lactams, oximes, hydroxylamines, and hydroperoxides. It can be used as a reagent for the preparation of N-methyl alkyl- and aryl-substituted amines, amides, and quaternary ammonium salts. Dimethyl sulfate is also used in the methylation of sulfur-containing compounds to synthesize sulfides and sulfonium ions.
It can also be used as a reagent:       

• For the preparation of quaternary ammonium acrylic monomer as a potent antibacterial agent by the quaternization of 2-dimethylamino ethyl methacrylate.       
• Along with dimethyl sulfoxide for the synthesis of epoxides from aldehydes and ketones via formation of trimethylsulfonium cation.      
• To prepare an oxygenate additive for diesel by the methylation of glycerol.

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08,GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H301,H314,H317,H330,H341,H350
• Conseils de prudence: P202 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 181.4 °F - closed cup
• Point d'éclair (°C): 83 °C - closed cup
• Équipement de protection individuelle: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter