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59588-U

Supelco

Discovery® C8 (5 µm) HPLC Columns

L × I.D. 2 cm × 2.1 mm Supelguard Guard Cartridge, pkg of 2 ea, Guard Cartridge holder required for use

Synonym(s):

C8 TM=["Supelguard"]guard column

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Discovery® C8 Supelguard Guard Cartridge, 5 μm particle size, L × I.D. 2 cm × 2.1 mm

material

stainless steel column

Agency

suitable for USP L7

product line

Discovery®

feature

endcapped

packaging

pkg of 2 ea

technique(s)

HPLC: suitable
LC/MS: suitable

L × I.D.

2 cm × 2.1 mm

surface area

200 m2/g

matrix

fully porous particle

matrix active group

C8 (octyl) phase

particle size

5 μm

pore size

180 Å

operating pH

2-8

application(s)

food and beverages

separation technique

reversed phase

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Legal Information

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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Hugo M Botelho et al.
Scientific reports, 5, 9038-9038 (2015-03-13)
Plasma membrane proteins are essential molecules in the cell which mediate interactions with the exterior milieu, thus representing key drug targets for present pharma. Not surprisingly, protein traffic disorders include a large range of diseases sharing the common mechanism of
Bo-Rui Kang et al.
Bioorganic & medicinal chemistry letters, 25(24), 5808-5812 (2015-11-08)
2-Benzylisoquinolin-1(2H)-ones has been proposed as vasodilative agents on the basis of scaffold hopping. In the present study, a series of 2-benzylisoquinolin-1(2H)-ones were synthesized. Their vasodilative effects were evaluated by wire myograph on isolated rat mesenteric arterial ring induced contraction with
Scott C Bell et al.
Pharmacology & therapeutics, 145, 19-34 (2014-06-17)
With the discovery of the CFTR gene in 1989, the search for therapies to improve the basic defects of cystic fibrosis (CF) commenced. Pharmacological manipulation provides the opportunity to enhance CF transmembrane conductance regulator (CFTR) protein synthesis and/or function. CFTR
H Jayasuriya et al.
Journal of natural products, 55(5), 696-698 (1992-05-01)
Bioassay-directed fractionation of a Chinese medicinal plant, Polygonum cuspidatum (Polygonaceae), has led to the discovery of an anthraquinone, emodin [1], as a strong inhibitor of a protein tyrosine kinase (p56lck) partially purified from bovine thymus. Comparison of the IC50 values
J Reniers et al.
European journal of medicinal chemistry, 46(12), 6104-6111 (2011-10-25)
Previous studies on 5H-indeno[1,2-c]pyridazin-5-one derivatives as inhibitors of MAO-B revealed that it was possible to increase the MAO-B inhibitory potency of 5H-indeno[1,2-c]pyridazin-5-ones by substituting the central heterocycle in the 3-position or C-8 with lipophilic groups which occupy the substrate cavity

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