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H2393

Sigma-Aldrich

HEPES sodium salt hydrate

≥99% (titration)

Synonym(s):

N-(2-Hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid) hemisodium salt

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About This Item

Linear Formula:
C8H17N2O4SNa
CAS Number:
Molecular Weight:
260.29
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:

Assay

≥99% (titration)

form

powder

useful pH range

6.8-8.2

 

7.5

pKa 

7.5

solubility

water: 500 mg/mL, clear, colorless to faintly yellow

storage temp.

room temp

SMILES string

O.[Na+].OCCN1CCN(CC1)CCS([O-])(=O)=O

InChI

1S/C8H18N2O4S.Na.H2O/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14;;/h11H,1-8H2,(H,12,13,14);;1H2/q;+1;/p-1

InChI key

ZNJHFNUEQDVFCJ-UHFFFAOYSA-M

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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A highly fluorescent Zn(2+) complex of the triazole linked salicyl-imino-thiophenyl conjugate of calix[4]arene, [ZnL] has been demonstrated to be a chemo-sensing ensemble for the recognition of His and Cys among the naturally occurring amino acids in HEPES buffer milieu. The
J R Eidet et al.
Experimental eye research, 94(1), 109-116 (2011-12-14)
The use of amniotic membrane (AM) represents one of the major developments in ocular surface reconstruction. However, in a study on patients with primary pterygium, transplantation of AM with ex vivo expanded human conjunctival epithelial cells (HCjE) promoted earlier epithelialization
Qing Dai et al.
Analytical chemistry, 83(17), 6559-6564 (2011-08-02)
A ratiometric fluorescence sensor based on pyrene was designed for selective detection of heparin in HEPES (N-(2-hydroxyethyl)piperazine-N'-ethanesulfonic acid) buffer and serum sample. Pyrene and long-chain alkanes were linked through bisquaternary functionality in the sensor which could interact with heparin via
Darren Locke et al.
The Journal of general physiology, 138(3), 321-339 (2011-08-17)
The mechanisms of action of endogenous modulatory ligands of connexin channels are largely unknown. Previous work showed that protonated aminosulfonates (AS), notably taurine, directly and reversibly inhibit homomeric and heteromeric channels that contain Cx26, a widely distributed connexin, but not

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