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NCXAUXR40

Sigma-Aldrich

Gold Nanospheres

40 nm, for Covalent Conjugation, Bioready, Carboxyl, OD 20, in Water

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About This Item

UNSPSC Code:
12162002
NACRES:
NA.23

form

nanospheres

OD

20

particle size

40 nm

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Application

Gold Nanosphere (40 nm, for covalent conjugation, Bioready, carboxyl, OD 20, in water) can be potentially used in the applications such as drug delivery, photoacoustic imaging, electrochemical immunosensors, and surface plasmon nanopatterning.
Owing to their plasmonic properties nanoparticles of gold and silver find broad range of applications extending from diagnostics to molecular detection, photothermal and microwave-based therapies, and nanotoxicology. Colloidal silver nanoparticles also find applications in antimicrobial coatings, electronics and photovoltaics, and surface enhanced Raman spectroscopy (SERS) whereas the colloidal gold nanoparticles find applications in lateral flow assays (immunochromatographic assays) and as TEM labels and size standards.

Our BioReady materials are engineered for reliable conjugation with antibodies, proteins, peptides, and other biomolecules and are ideal for lateral flow (immunochromatographic assays) and other diagnostics related applications.

The BioReady spherical gold nanoparticles with carboxyl surface can be used for robust covalent conjugation. This allows for greater stability, sensitivity, reproducibility, and control over particle antibody loading (often requires less antibody compared to passive adsorption). Our covalently-bound streptavidin conjugated gold nanoparticles allow easy binding with biotin.

The BioReady conjugation kits contain dried gold nanoparticles with NHS-activated carboxyl surface. With pre-functionalized nanoparticles with EDC/NHS surface, these are well suited for rapid antibody screening.
The small reaction NHS kits contain 50 μL of 20 OD gold in each unit whereas the large reaction kits contain 500 μL of 20 OD gold in each unit.

Storage and Stability

DO NOT FREEZE. Store at 2-8C when not in use to maximize shelf life. Nanomaterials can be sensitive to high and low pH conditions and high salt concentrations. Use caution when changing environmental conditions as particles may aggregate.

Legal Information

Product of nanoComposix, Inc.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Photoacoustic imaging of living mouse brain vasculature using hollow gold nanospheres
Lu W, et al.
Biomaterials, 31(9), 2617-2626 (2010)
Ultrasensitive electrochemical immunosensor for clinical immunoassay using thionine-doped magnetic gold nanospheres as labels and horseradish peroxidase as enhancer
Tang D, et al.
Analytical Chemistry, 80(5), 1582-1588 (2008)
Surface plasmon-based nanopatterning assisted by gold nanospheres
Heltzel A, et al.
Nanotechnology, 19(2), 025305-025305 (2007)
Exceptionally high payload of doxorubicin in hollow gold nanospheres for near-infrared light-triggered drug release
You J, et al.
ACS Nano, 4(2), 1033-1041 (2010)

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