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D80800

Sigma-Aldrich

N,N′-Dicyclohexylurea

98%

Synonym(s):

1,3-Dicyclohexylurea

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About This Item

Linear Formula:
C6H11NHCONHC6H11
CAS Number:
2387-23-7
Molecular Weight:
224.34
EC Number:
219-213-7
MDL number:
MFCD00003829
UNSPSC Code:
12352100
PubChem Substance ID:
24894186
NACRES:
NA.22

Assay

98%

form

solid

mp

232-233 °C (lit.)

SMILES string

O=C(NC1CCCCC1)NC2CCCCC2

InChI

1S/C13H24N2O/c16-13(14-11-7-3-1-4-8-11)15-12-9-5-2-6-10-12/h11-12H,1-10H2,(H2,14,15,16)

InChI key

ADFXKUOMJKEIND-UHFFFAOYSA-N

Gene Information

human ... EPHX2(2053)
mouse ... Ephx2(13850)

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Michele Aresta et al.
Dalton transactions (Cambridge, England : 2003), 39(30), 6985-6992 (2010-06-15)
NbCl(5) x (N,N'-dicyclohexylurea) 1a owns a distorted octahedral structure due to intramolecular NH...Cl bonding. The unit cell contains four units which are intermolecularly NH...Cl and NH...N bonded. An extended intramolecular network of H-bonding (N-H...Cl, CH...Cl, CH...N) causes the 3D self
T Watanabe et al.
Analytical biochemistry, 299(2), 227-234 (2001-12-04)
A rapid and reliable electrospray tandem mass spectrometric method for soluble epoxide hydrolase (sEH) inhibitors in rat hepatic microsomes is described. Four synthesized sEH inhibitors were extracted from rat hepatic microsomes with ethyl acetate and were determined by HPLC using
Sarbani Ghosh et al.
Basic & clinical pharmacology & toxicology, 102(5), 453-458 (2008-03-04)
Cytochrome P450-derived epoxyeicosatrienoic acids (EET) are biologically active metabolites of arachidonic acid that have potent effects on renal vascular reactivity and tubular ion transport and have been implicated in the control of blood pressure. EETs are hydrolyzed to their less
Mozhgan Aghajanzadeh et al.
International journal of pharmaceutics, 586, 119546-119546 (2020-06-17)
In the present study, we successfully synthesized nanocarriers (NCs) based on Y-shaped miktoarm copolymers, Poly Ethylene Glycol-Lysine-(Poly Caprolactone)2 (PEG-Lys-PCL2), which were loaded by baicalein (B) through the nanoprecipitation process to assess their in-vitro and in-vivo properties. We applied various methods
Xiang Fang et al.
American journal of physiology. Heart and circulatory physiology, 290(1), H55-H63 (2005-08-23)
Epoxyeicosatrienoic acids (EETs), lipid mediators synthesized from arachidonic acid by cytochrome P-450 epoxygenases, are converted by soluble epoxide hydrolase (SEH) to the corresponding dihydroxyeicosatrienoic acids (DHETs). Originally considered as inactive degradation products of EETs, DHETs have biological activity in some
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