L9650

Lithium chloride

for molecular biology, ≥99%

• Synonym(s): LiCl
• Linear Formula: LiCl
• CAS Number: 7447-41-8
• Molecular Weight: 42.39
• EC Number: 231-212-3
• MDL number: MFCD00011078
• UNSPSC Code: 12352302
• PubChem Substance ID: 24896459
• NACRES: NA.31

Properties

• grade: for molecular biology
• Assay: ≥99%
• form: powder
• mp: 605 °C (lit.)
• solubility: H₂O: 100 mg/mL at 20 °C, clear, colorless
• anion traces: sulfate (SO₄^2-): ≤0.01%
• cation traces: Ba: ≤0.003%; Fe: ≤0.001%; K: ≤0.01%; Na: ≤0.20%; heavy metals (as Pb): ≤0.002%
• foreign activity: DNase, NICKase, RNase, protease, none detected
• SMILES string: [Li+].[Cl-]
• InChI: 1S/ClH.Li/h1H;/q;+1/p-1
• InChI key: KWGKDLIKAYFUFQ-UHFFFAOYSA-M

Description

Application

Lithium chloride has been used:

• in the preparation of wash buffer for chromatin immunoprecipitation
• in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay
• to treat aged myoblast as glycogen synthase kinase (GSK) inhibitor to analyse its effect on wingless/tailess (wnt) signaling

May be used to selectively pre­cipitate RNA.

Biochem/physiol Actions

Lithium chloride has the ability to block glycogen synthase kinase (GSK). It may also possess anti-inflammatory effects at low and non-toxic concentrations.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319
• Precautionary Statements: P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves