33987
Olaquindox
VETRANAL®, analytical standard
Synonym(s):
N-(2-Hydroxyethyl)-3-methyl-2-quinoxalinecarboxamide 1,4-dioxide
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About This Item
Empirical Formula (Hill Notation):
C12H13N3O4
CAS Number:
Molecular Weight:
263.25
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
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grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
Cc1c(C(=O)NCCO)[n+]([O-])c2ccccc2[n+]1[O-]
InChI
1S/C12H13N3O4/c1-8-11(12(17)13-6-7-16)15(19)10-5-3-2-4-9(10)14(8)18/h2-5,16H,6-7H2,1H3,(H,13,17)
InChI key
TURHTASYUMWZCC-UHFFFAOYSA-N
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General description
Olaquindox is an antibiotic veterinary drug, used as a growth promoter for pig farming.
Application
Olaquindox may be used as a reference standard in the determination of olaquindox in feed samples using matrix solid-phase dispersion extraction (MSPDE) and hydrophilic interaction ultra-high-pressure liquid chromatography (HILIC-UHPLC) with photodiode array detector.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Resp. Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Xu Wang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 49(5), 1068-1079 (2011-01-27)
To investigate the teratogenic potential and reproductive toxicity of cyadox, a growth promoting agent, Wistar rats (F(0)) were fed with diets containing cyadox (0, 50, 150 and 2500 mg/kg) or olaquindox (150 mg/kg), approximately equivalent to cyadox 5, 15, 250
Xian-Ju Huang et al.
Chemico-biological interactions, 185(3), 227-234 (2010-03-02)
Quinoxaline 1,4-dioxides (QdNOs) derivatives, the potent synthetic antibacterial group used in food-producing animals, are assumed to have pro-oxidant properties. However, how oxidative stress mediated their adrenal toxicity is far from clear. The aim of this study was to assess the
Biodegradability of metronidazole, olaquindox, and tylosin and formation of tylosin degradation products in aerobic soil--manure slurries
Ingerslev F and Halling-Sorensen B
Ecotoxicology and Environmental Safety, 48(3), 311-320 (2001)
Tianci Xu et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(7), 2540-2546 (2012-04-25)
The interaction between olaquindox (OLA) and bovine serum albumin (BSA) was investigated using fluorescence, UV-vis absorption and circular dichroism (CD) spectroscopy. The results showed that the fluorescence quenching of BSA by OLA was a static quenching process induced by the
Xu Wang et al.
Regulatory toxicology and pharmacology : RTP, 59(2), 324-333 (2010-12-07)
To investigate the chronic toxicity of cyadox, a growth promoting agent, five groups of Wistar rats (30 rats/group/sex) were fed with the diets containing cyadox (0, 100, 400 and 2000 mg/kg) or olaquindox (400 mg/kg) for 78weeks. There were significant
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