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Key Documents

05-5160

Sigma-Aldrich

Cobalt(II) chloride hexahydrate

SAJ first grade, ≥95.0%

Synonym(s):

Cobaltous chloride hexahydrate

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About This Item

Linear Formula:
CoCl2 · 6H2O
CAS Number:
Molecular Weight:
237.93
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:

grade

SAJ first grade

vapor pressure

40 mmHg ( 0 °C)

Assay

≥95.0%

form

solid

reaction suitability

reagent type: catalyst
core: cobalt

availability

available only in Japan

SMILES string

O.O.O.O.O.O.Cl[Co]Cl

InChI

1S/2ClH.Co.6H2O/h2*1H;;6*1H2/q;;+2;;;;;;/p-2

InChI key

GFHNAMRJFCEERV-UHFFFAOYSA-L

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Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B Inhalation - Eye Dam. 1 - Muta. 2 - Repr. 1B - Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Gláucia Melo Reis et al.
Pharmacology, biochemistry, and behavior, 131, 112-118 (2015-02-18)
The stimulation of the retrosplenial cortex (RSC) is antinociceptive in the rat tail-flick and formalin tests. The rat RSC is caudal to and send projections to the ipsilateral anterior cingulate cortex (ACC), which is also involved in pain processing. This
H Lawrence et al.
The bone & joint journal, 96-B(9), 1172-1177 (2014-09-04)
Abnormal wear of cobalt-containing metal-on-metal joints is associated with inflammatory pseudotumours. Cobalt ions activate human toll-like receptor 4 (TLR4), which normally responds to bacterial lipopolysaccharide (LPS) in sepsis. Activation of TLR4 by LPS increases the expression of chemokines IL-8 and
Junya Nagai et al.
Biochemical and biophysical research communications, 450(1), 476-481 (2014-06-14)
Recently, we found that albumin overload induces expression of the transcription factor hypoxia-inducible factor-1α (HIF-1α) protein and several HIF-1 target genes in human renal proximal tubular epithelial cell line HK-2. In this study, the role of albumin-bound fatty acids in
Qingpo Li et al.
Biomaterials, 57, 1-11 (2015-05-10)
Antibody-mediated targeting therapy has been successful in treating patients with cancers by improving the specificity and clinical efficacy. In this study, we developed a human epidermal growth factor receptor-2 (HER2) antibody-conjugated drug delivery system, using near-infrared (NIR) light-sensitive liposomes containing
Björn Koos et al.
Nature communications, 6, 7294-7294 (2015-06-13)
Sensitive detection of protein interactions and post-translational modifications of native proteins is a challenge for research and diagnostic purposes. A method for this, which could be used in point-of-care devices and high-throughput screening, should be reliable, cost effective and robust.

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