8.20261

8-Hydroxyquinoline

for synthesis

• Synonym(s): 8-Hydroxyquinoline, Oxine, 8-Quinolinol
• Empirical Formula (Hill Notation): C₉H₇NO
• CAS Number: 148-24-3
• Molecular Weight: 145.16
• UNSPSC Code: 12352104
• EC Index Number: 205-711-1
• NACRES: NA.22
• MDL number: MFCD00006807

Properties

• Quality Segment: 200
• assay: ≥99.0% (GC)
• form: solid
• potency: 1200 mg/kg LD₅₀, oral (Rat)
• reaction suitability: reaction type: Addition Reactions
• bp: 267 °C/1013 hPa
• mp: 72.5-74.0 °C
• solubility: 555 mg/L
• density: 1.034 g/cm³ at 20 °C
• application(s): peptide synthesis
• storage temp.: 2-30°C
• SMILES string: n1c2c(ccc1)cccc2O
• InChI: 1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H
• InChI key: MCJGNVYPOGVAJF-UHFFFAOYSA-N

Description

Application

<ul>
<li><strong>8-Hydroxyquinoline in luminescent cocrystals for analytical detection:</strong> 8-Hydroxyquinoline is used as an electron donor during the development of luminescent organic cocrystal for the detection of 2,4-dinitroaniline, demonstrating its utility in analytical chemistry applications (Liu et al., 2024).</li>
<li><strong>Extraction and determination of pesticides using 8-Hydroxyquinoline functionalized nanocomposites:</strong> Poly(8-hydroxyquinoline) were utilized for the extraction and determination of organophosphorus pesticides in various environmental samples, showcasing its application in environmental monitoring (Shahsavani and Fakhari, 2024).</li>
<li><strong>8-Hydroxyquinoline in medical imaging and therapy:</strong> 8-Hydroxyquinoline is used as a Schiff base derivative and an auxiliary ligand in the synthesis of the dinuclear lanthanide complex [Ho2(L)2(acac)2(CH3OH)2] (Cong et al., 2024).</li>
</ul>

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Melting range (lower value): ≥ 71 °C
Melting range (upper value): ≤ 74 °C
Identity (IR): passes test

Safety Information

• pictograms: GHS05,GHS06,GHS08,GHS09
• signalword: Danger
• hcodes: H301 - H317 - H318 - H360D - H410
• pcodes: P202 - P273 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 1B - Skin Sens. 1
• Storage Class: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable