1.02465

Calcium chloride dihydrate

EMPROVE^® API, Ph. Eur., BP, ChP, JP, USP

• Synonym(s): Calcium dichloride
• Empirical Formula (Hill Notation): CaCl₂ · 2H₂O
• CAS Number: 10035-04-8
• Molecular Weight: 147.01
• UNSPSC Code: 12352302
• EC Index Number: 600-075-5
• MDL number: MFCD00149613

Properties

• Quality Level: 600
• agency: BP, ChP, JP, Ph. Eur., USP
• product line: EMPROVE^® API
• form: solid
• potency: 2630 mg/kg LD₅₀, skin (Rat)
• pH: 4.5-8.5 (20 °C, 50 g/L in H₂O)
• mp: 176 °C (dec.) (lit.)
• solubility: soluble
• application(s): liquid formulation; ophthalmics; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 2-25°C
• SMILES string: O.O.Cl[Ca]Cl
• InChI: 1S/Ca.2ClH.2H2O/h;2*1H;2*1H2/q+2;;;;/p-2
• InChI key: LLSDKQJKOVVTOJ-UHFFFAOYSA-L

Description

General description

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Calcium chloride dihydrate is typically used in clinical nutrition and in infusion. Calcium Chloride dihydrate cryst. Emprove^® API is manufactured according to ICH Q7 guidelines. A CEP and an US-DMF are available.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 13 - Non Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable