Homochiral porous organic cage used as stationary phase for open tubular capillary electrochromatography.

Porous organic molecular cages, as a new type of porous materials, have in recent years attracted a tremendous amount of attention for their potential applications. However, to the best of our knowledge, there has been no attempt to utilize porous organic molecular cages as stationary phases in capillary electrochromatography (CEC). We report herein the use of a homochiral porous organic cage (POC) (CC3-R) as a stationary phase in open tubular capillary electrochromatography (OT-CEC) for the separation of chiral compounds and positional isomers. The column was fabricated using CC3-R as the stationary phase by a static coating method. Separation of furoin, benzoin, and alprenlol were achieved on the CC3-R coated column, with the highest resolution value (R