- Characterization of sodium-selective optode membranes based on neutral ionophores and assay of sodium in plasma.
Characterization of sodium-selective optode membranes based on neutral ionophores and assay of sodium in plasma.
Clinical chemistry (1991-08-01)
K Seiler, K Wang, E Bakker, W E Morf, B Rusterholz, U E Spichiger, W Simon
PMID1868594
ABSTRACT
Plasticized poly(vinyl chloride) membranes that incorporate a highly lipophilic sodium-selective neutral ionophore (ETH 4120) and novel H(+)-selective chromo-ionophores, lipophilic isologs of Nile Blue, are used in the competitive binding of Na+ and H+ for a reversible, optical determination of sodium activities in buffered solutions at different selected pH values. These optode membranes are used to assay total sodium concentrations in pH-buffered human blood plasma.
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