- Dexmedetomidine to treat lisdexamfetamine overdose and serotonin toxidrome in a 6-year-old girl.
Dexmedetomidine to treat lisdexamfetamine overdose and serotonin toxidrome in a 6-year-old girl.
American journal of critical care : an official publication, American Association of Critical-Care Nurses (2012-11-03)
Olugbenga A Akingbola, Dinesh Singh
PMID23117910
ABSTRACT
A 6-year-old girl displayed symptoms of serotonin syndrome after accidental ingestion of Vyvanse (lisdexamfetamine dimesylate). Dexmedetomidine was administered because of persistent neuromuscular hyperactivity and severe agitation despite initial therapy with benzodiazepines. Some children show a paradoxical reaction to benzodiazepines, and dexmedetomidine has a possible role in the treatment of serotonin syndrome.
MATERIALS
Product Number
Brand
Product Description
Supelco
Lorazepam solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
Lorazepam, European Pharmacopoeia (EP) Reference Standard
Lorazepam for system suitability, European Pharmacopoeia (EP) Reference Standard