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Key Documents

286567

Sigma-Aldrich

Mephenesin

98%

Synonym(s):

3-(2-Methylphenoxy)-1,2-propanediol

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About This Item

Linear Formula:
CH3C6H4OCH2CH(OH)CH2OH
CAS Number:
Molecular Weight:
182.22
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.25

Assay

98%

form

powder

bp

153-154 °C/4 mmHg (lit.)

mp

69-71 °C (lit.)

SMILES string

Cc1ccccc1OCC(O)CO

InChI

1S/C10H14O3/c1-8-4-2-3-5-10(8)13-7-9(12)6-11/h2-5,9,11-12H,6-7H2,1H3

InChI key

JWDYCNIAQWPBHD-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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S Bertrand et al.
The European journal of neuroscience, 11(2), 583-592 (1999-03-03)
The in vitro newborn rat isolated brain stem/spinal cord preparation was used to study the involvement of presynaptic inhibition in the control of the synaptic locomotor drive. The recording chamber was partitioned with Vaseline walls to separate the L1-L2 locomotor
C Beltran et al.
Annales de dermatologie et de venereologie, 136(10), 709-712 (2009-10-06)
In most cases, acute generalized exanthematous pustulosis (AGEP) is a drug reaction. Even if several systemic drugs have been reported to be a causative agent, this clinical case has rarely been observed with a topical treatment. We report here a
M A Shuker et al.
British journal of pharmacology, 111(3), 951-955 (1994-03-01)
1. Previous studies have suggested that a series of drugs modelled on part of the strychnine molecule interfere with the development of high pressure neurological syndrome (HPNS) and it was presumed that this effect was via an action on inhibitory
B Nickel et al.
Arzneimittel-Forschung, 40(8), 909-911 (1990-08-01)
The influence of the skeletal muscle tone by flupirtine (D-9998, Katadolon; CAS 56995-20-1), some selected analgesics and muscle relaxants was investigated in conscious rats after intraperitoneal administration. Benzodiazepines (diazepam and tetrazepam), baclofen, dantrolene and mephenesine reduced the tone of the
Shohei Yamamoto et al.
Brain research, 1082(1), 115-123 (2006-03-02)
Nociceptive signals are transmitted to the spinal dorsal horn via primary afferent fibers, and the signals induce withdrawal reflexes by activating spinal motoneurons in the ventral horn. Therefore, nociceptive stimuli increase motoneuronal firing and ventral root discharges. This study was

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