Skip to Content
Merck
All Photos(1)

Documents

197173

Sigma-Aldrich

2-Hydrazino-2-imidazoline hydrobromide

98%

Synonym(s):

2-Hydrazino-4,5-dihydroimidazole hydrobromide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C3H8N4 · HBr
CAS Number:
55959-84-7
Molecular Weight:
181.03
EC Number:
259-921-3
MDL number:
MFCD00012694
UNSPSC Code:
12352100
PubChem Substance ID:
24851339
NACRES:
NA.22

Assay

98%

mp

185-187 °C (lit.)

SMILES string

Br.NNC1=NCCN1

InChI

1S/C3H8N4.BrH/c4-7-3-5-1-2-6-3;/h1-2,4H2,(H2,5,6,7);1H

InChI key

HIJRJVVSABWXKG-UHFFFAOYSA-N

Application

2-Hydrazino-2-imidazoline hydrobromide was used in synthesis of:
  • some amide derivatives of 6-(4-carboxymethyloxyphenyl)-4,5-dihydro-3(2H)-pyridazinone
  • 2-substituted-6-(4-acylaminophenyl)-4,5-dihydropyridazin-3(2H)-ones, potential inodilating agents
Reactant for synthesis of:
  • Molecules that affect vasodilatory activity
  • Sulfate-bridges dimerica copper(II) complexes
  • 5-HT6 serotonin receptor antagonists
  • Pd complexes
  • Antidiabetic/antiobesity agents
  • DNA binders

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Dinesh Kumar et al.
Acta pharmaceutica (Zagreb, Croatia), 58(4), 393-405 (2008-12-24)
The present study describes the synthesis and pharmacological evaluation of 2-substituted-6-(4-acylaminophenyl)-4,5-dihydropyridazin-3(2H)-ones as potent inodilating agents. The synthesis of target compounds 2-4 and 7-11 was achieved by Friedel-Crafts acylation of appropriate anilide derivative with succinic anhydride or methylsuccinic anhydride and subsequent
Ranju Bansal et al.
European journal of medicinal chemistry, 44(11), 4441-4447 (2009-07-11)
Synthesis and vasodilatory activity of some amide derivatives of 6-(4-carboxymethyloxyphenyl)-4,5-dihydro-3(2H)-pyridazinone are reported. An effect of substitution at 2-position of pyridazinone ring on vasodilatory potential has also been explored. The most active compound 6-[4-(2-oxo-2-pyrrolidin-1-yl-ethoxy)phenyl]-2-(4-fluorophenyl)-4,5-dihydropyridazin-3(2H)-one (11) exhibited vasodilating activity in nanomolar range
Mohamed A Hashem et al.
Carbohydrate polymers, 237, 116177-116177 (2020-04-04)
A new hydrazono-imidazoline modified cellulose (HIMC) was synthesized for selective recovery of Pt(IV), Pd(II) and Au(III) from geological samples. Cellulose was oxidized by periodate and was further functionalized with hydrazono-imidazoline moieties to afford N-donor chelating fibers. Scanning electron microscopy (SEM)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service