Skip to Content
Merck

SIGLEC1

sialic acid binding Ig-like lectin 1, sialoadhesin

Synonyms:
CD169, SIGLEC-1, SN, dJ1009E24.1
Species:
UniProtKB ID:
Gene ID:
  • Human(6614) Summary: This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(20612) sialic acid binding Ig-like lectin 1, sialoadhesin
  • Rat(311426) sialic acid binding Ig-like lectin 1, sialoadhesin
  • dog(485794) sialic acid binding Ig-like lectin 1, sialoadhesin
  • domestic cat(101093264) sialic acid binding Ig-like lectin 1, sialoadhesin
  • Horse(100066351) sialic acid binding Ig-like lectin 1, sialoadhesin
  • Domestic Rabbit(100345836) sialic acid binding Ig-like lectin 1, sialoadhesin
  • domestic guinea pig(100713768) sialic acid binding Ig-like lectin 1, sialoadhesin
  • sheep(101110959) sialic acid binding Ig-like lectin 1, sialoadhesin
  • cow(539759) sialic acid binding Ig-like lectin 1, sialoadhesin
  • naked mole-rat(101698560) sialic acid binding Ig-like lectin 1, sialoadhesin

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
Human Siglec-1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD169/Siglec1 antibody produced in mouse, clone 7-239,
Species Reactivity
human
Application
flow cytometry
Anti-CD169 antibody, Rabbit monoclonal, clone SP213, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-CD169 antibody, Rabbit monoclonal, clone SP216, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-CD169-APC antibody produced in mouse, clone 7-239,
Species Reactivity
Application
flow cytometry
Anti-SIGLEC1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SIGLEC1,
Species
human
MISSION® esiRNA, targeting mouse Siglec1,
Species
mouse