NPHS2
nephrosis 2, idiopathic, steroid-resistant (podocin)
Synonyms:
PDCN, SRN1
Species:
Human NPHS2 (7827), Mouse Nphs2 (170484), Rat Nphs2 (170672), Zebrafish nphs2 (557914), chicken NPHS2 (424422), dog NPHS2 (490323), sheep NPHS2 (101121618), cow NPHS2 (537633), domestic guinea pig Nphs2 (100716190), naked mole-rat Nphs2 (101704471)
UniProtKB ID:
Gene ID:
- Human(7827) Summary: This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
- Mouse(170484) nephrosis 2, podocin
- Rat(170672) nephrosis 2, idiopathic, steroid-resistant
- Zebrafish(557914) nephrosis 2, idiopathic, steroid-resistant (podocin)
- chicken(424422) nephrosis 2, idiopathic, steroid-resistant (podocin)
- dog(490323) nephrosis 2, idiopathic, steroid-resistant (podocin)
- sheep(101121618) nephrosis 2, idiopathic, steroid-resistant (podocin)
- cow(537633) nephrosis 2, idiopathic, steroid-resistant (podocin)
- domestic guinea pig(100716190) nephrosis 2, idiopathic, steroid-resistant (podocin)
- naked mole-rat(101704471) nephrosis 2, idiopathic, steroid-resistant (podocin)
- domestic cat(101084927) nephrosis 2, idiopathic, steroid-resistant (podocin)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NPHS2 Antibody, clone 2O10G3, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot
Anti-Podocin, Mouse monoclonal, clone PD-65, purified from hybridoma cell culture,
Species Reactivity
bovine, human, mouse, rat
Application
immunofluorescence
western blot
western blot
Anti-NPHS2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-NPHS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Podocin antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot
western blot
esiRNA
Product Number
Description
Species