KREMEN2
kringle containing transmembrane protein 2
Synonyms:
KRM2
Species:
Human KREMEN2 (79412), Mouse Kremen2 (73016), Rat Kremen2 (287102), naked mole-rat Kremen2 (101720049), domestic cat KREMEN2 (101098677), sheep KREMEN2 (101119273), domestic guinea pig Kremen2 (100734476), cow KREMEN2 (618527), dog KREMEN2 (610753)
UniProtKB ID:
Gene ID:
- Human(79412) Summary: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
- Mouse(73016) kringle containing transmembrane protein 2
- Rat(287102) kringle containing transmembrane protein 2
- naked mole-rat(101720049) kringle containing transmembrane protein 2
- domestic cat(101098677) kringle containing transmembrane protein 2
- sheep(101119273) kringle containing transmembrane protein 2
- domestic guinea pig(100734476) kringle containing transmembrane protein 2
- cow(618527) kringle containing transmembrane protein 2
- dog(610753) kringle containing transmembrane protein 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-KREMEN2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-KREMEN2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
esiRNA
Product Number
Description
Species