- One-step synthesis of diarylpyrazolo[3,4-b]pyridines from isoflavones.
One-step synthesis of diarylpyrazolo[3,4-b]pyridines from isoflavones.
Journal of combinatorial chemistry (2010-06-08)
Zun-Ting Zhang, Yong Liang, Yu-Qing Ma, Dong Xue, Jun-Ling Yang
PMID20524639
ABSTRACT
A new concise, facile, and efficient method for the synthesis of 3-hydroxy-5,6-diphenylpyrazolo[3,4-b]pyridine derivatives has been described. The cyclocondensation of isoflavones with 3-amino-5-hydroxypyrazole in the presence of sodium methoxide gave fused heteroaromatic 3-hydroxy-5,6-diphenylpyrazolo[3,4-b]pyridines in moderate to good yields.
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