- Optimization of a series of multi-isoform PI3 kinase inhibitors.
Optimization of a series of multi-isoform PI3 kinase inhibitors.
Bioorganic & medicinal chemistry letters (2008-09-09)
Benjamin Perry, Rebekah Beevers, Gavin Bennett, George Buckley, Tom Crabbe, Lewis Gowers, Lynwen James, Kerry Jenkins, Chris Lock, Verity Sabin, Sara Wright
PMID18774713
ABSTRACT
Optimization of the cellular and pharmacological activity of a novel series of PI3 kinase inhibitors targeting multiple isoforms is described.
MATERIALS