SML0669

VUF11207 trifluoroacetate salt

≥98% (HPLC)

• Synonym(s): (E)-N-(3-(2-Fluorophenyl)-2-methylallyl)-3,4,5-trimethoxy-N-(2-(1-methylpyrrolidin-2-yl)ethyl)benzamide trifluoroacetate salt, N-[(2E)-3-(2-Fluorophenyl)-2-methyl-2-propen-1-yl]-3,4,5-trimethoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-benzamide trifluoroacetate salt
• Empirical Formula (Hill Notation): C₂₇H₃₅FN₂O₄ · C₂HF₃O₂
• CAS Number: 1378524-41-4
• Molecular Weight: 584.60
• MDL number: MFCD26961112
• UNSPSC Code: 51111800
• PubChem Substance ID: 329825579
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• storage condition: desiccated; protect from light
• color: white to beige
• solubility: H₂O: 5 mg/mL, clear (warmed)
• storage temp.: −20°C
• SMILES string: O=C(N(CCC1N(C)CCC1)C/C(C)=C/C2=C(F)C=CC=C2)C3=CC(OC)=C(OC)C(OC)=C3.OC(C(F)(F)F)=O
• InChI: 1S/C27H35FN2O4.C2HF3O2/c1-19(15-20-9-6-7-11-23(20)28)18-30(14-12-22-10-8-13-29(22)2)27(31)21-16-24(32-3)26(34-5)25(17-21)33-4;3-2(4,5)1(6)7/h6-7,9,11,15-17,22H,8,10,12-14,18H2,1-5H3;(H,6,7)/b19-15+;
• InChI key: GZXNWMFPSYCITC-QTCZRQAZSA-N

Description

Biochem/physiol Actions

VUF11207 is a highly potent CXCR7 agonist. VUF11207 induces recruitment of β-arrestin2 to the CXCR7 followed by internalization of the receptor.

VUF11207 is considered as a selective inhibitor of CXCR4 (C-X-C motif chemokine receptor 4).

Other Notes

Hygroscopic and light sensitive

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable