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852758P

Avanti

C18(Plasm)-18:1 PE

1-(1Z-octadecenyl)-2-oleoyl-sn-glycero-3-phosphoethanolamine, powder

Synonym(s):

1-O-1′-(Z)-octadecenyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; GPEtn(18:0p/18:1(9Z)); 110645

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About This Item

Empirical Formula (Hill Notation):
C41H80NO7P
CAS Number:
144371-68-6
Molecular Weight:
730.05
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (852758P-10mg)
pkg of 1 × 5 mg (852758P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 852758P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[NH3+])(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)CO/C=C\CCCCCCCCCCCCCCCC)=O

General description

Phosphatidylethanolamine is an amino phospholipid, which is found in eukaryotic and prokaryotic cells. It is one of the most abundant glycerophospholipids in the biological membranes. Phosphatidylethanolamine is found in nervous tissue.

Application

C18(Plasm)-18:1 PE has been used for lipid purification and fatty acid extraction. It has also been used for lipopolysaccharide (LPS)-mediated beta rich prion protein PrPβ conversion.

Biochem/physiol Actions

Phosphatidylethanolamine forms pure lipid structures. It maintains membrane fluidity in eukaryotic cells. Phosphatidylethanolamine plays a critical role in autophagy, cell division and protein folding. It acts as a precursor for the synthesis of various protein modifications. Phosphatidylethanolamine functions as an intermediate for the synthesis of glycerophospholipid classes.

Packaging

5 mL Amber Glass Screw Cap Vial (852758P-5mg)
5 mL Amber Glass Sealed Ampule (852758P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The Membranes of Cells (2016)
An Introduction to Biological Membranes: Composition, Structure and Function (2016)
Nathan R Deleault et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(28), E1938-E1946 (2012-06-20)
Prions containing misfolded prion protein (PrP(Sc)) can be formed with cofactor molecules using the technique of serial protein misfolding cyclic amplification. However, it remains unknown whether cofactors materially participate in maintaining prion conformation and infectious properties. Here we show that
Lipopolysaccharide induced conversion of recombinant prion protein
Saleem F, et al.
Prion, 8(2), 221-232 (2014)
Detection of unusual very-long-chain fatty acid and ether lipid derivatives in the fibroblasts and plasma of patients with peroxisomal diseases using liquid chromatography-mass spectrometry
Takashima S, et al.
Molecular Genetics and Metabolism, 120(3), 255-268 (2017)
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