- Relative resistance of rabbits to MPTP neurotoxicity.
Relative resistance of rabbits to MPTP neurotoxicity.
Molecular and chemical neuropathology (1995-06-01)
N Lermontova, O Drany, D Dobrota, V Mezesova, V Lombardi, S Bachurin
PMID8534316
RÉSUMÉ
The neurotoxic actions of MPTP and its 4-(O-tolyl) analog (2'-Me-MPTP) on two breeds of rabbits were investigated. MPTP, but not 2'-Me-MPTP, causes a reduction (about 40%) in striatal dopamine content in rabbits of the "little silver-black" breed. The dopamine content of striata of "chinchilla" rabbits was not affected by either agent.
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