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[Inductive effects of enzymes of salicylic acid derivatives].

Comptes rendus des seances de la Societe de biologie et de ses filiales (1982-01-01)
H Goudonnet, J Mounié, K Bereksi-Reguig, R Truchot
RÉSUMÉ

In the series of salicylic acids derivatives investigated 3,5-DIS has a large inductive effect of enzymes with respect to the metabolism of xenobiotics: rise in the rate of Cyt. P 450; increase of ethoxycoumarin deethylase, bilirubin glucuronosyl transferase and benzphetamine-N-demethylase activities. This effect is comparable with that of phenobarbital.

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2-Hydroxy-4-iodobenzoic acid, ≥95%