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Merck

Development of biomimetic nano-hydroxyapatite/poly(hexamethylene adipamide) composites.

Biomaterials (2002-10-04)
Xuejiang Wang, Yubao Li, Jie Wei, Klass de Groot
RÉSUMÉ

In this study, acicular nano-hydroxyapatite (n-HA) was used to make a new biomimetic composite with polyamide (poly hexamethylene adipamide) by a unique technique. The physical and chemical characteristics of the composites were tested. It was found that these synthesized n-HA crystals were similar to bone apatite in size, phase composition and crystal structure. The biomimetic n-HA crystals were uniformly distributed in the polymer matrix and its content can reach 65%, close to that in natural bone. Chemical binding between inorganic n-HA and polyamide was investigated and discussed. The mechanical properties of the composites were found to match well with those of natural bone.

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Sigma-Aldrich
Adipamide, 98%