- Antiviral properties of ent-labdene diterpenes of Andrographis paniculata nees, inhibitors of herpes simplex virus type 1.
Antiviral properties of ent-labdene diterpenes of Andrographis paniculata nees, inhibitors of herpes simplex virus type 1.
Phytotherapy research : PTR (2005-12-24)
C Wiart, K Kumar, M Y Yusof, H Hamimah, Z M Fauzi, M Sulaiman
PMID16372376
RÉSUMÉ
Andrographolide, neoandrographolide and 14-deoxy-11,12-didehydroandrographolide, ent-labdene diterpenes isolated from Andrographis paniculata showed viricidal activity against herpes simplex virus 1 (HSV-1). None of these compounds exhibited significant cytotoxicity at viricidal concentrations.
MATÉRIAUX