A novel heterocyclic atom exchange reaction with Lawesson's reagent: a one-pot synthesis of dithiomaltol.

A novel heterocyclic atom exchange reaction with Lawesson's reagent: a one-pot synthesis of dithiomaltol.

Chemical communications (Cambridge, England) (2005-12-24)

Daniel Brayton, Faith E Jacobsen, Seth M Cohen, Patrick J Farmer

RÉSUMÉ

A one-pot reaction of maltol with Lawesson's reagent generates dithiomaltol, a thiopyran-4-thione, via an unusual heterocyclic atom exchange (HCAE) reaction; only pyrones with proton or aliphatic substituents undergo the HCAE substitution.

MATÉRIAUX

Référence du produit

Marque

Description du produit

227439

Sigma-Aldrich

Lawesson reagent, 97%