SRP8008

FTO mouse

recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE)

• Synonyme(s) : EC 1.14.11, FATSO, Fat mass and obesity-associated protein, Preadipocyte factor 1
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.32

Propriétés

• Source biologique: mouse
• Produit recombinant: expressed in E. coli
• Étiquette/Marqueur: His tagged
• Pureté: >90% (SDS-PAGE)
• Forme: liquid
• Poids mol.: ~55 kDa by SDS-PAGE
• Conditionnement: pkg of 10 μg
• Conditions de stockage: avoid repeated freeze/thaw cycles
• Concentration: ≥0.2 mg/mL
• Impuretés: <1 EU/μg endotoxin, tested
• Couleur: clear
• Numéro d'accès UniProt: Q8BGW1
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Informations sur le gène: mouse ... Fto(26383)

Description

Description générale

FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ′fused toes′ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

Forme physique

Solution in 55 mM TRIS-HCl, pH 8.2, containing 150 mM NaCl.

Autres remarques

Mouse FTO (aa 2-502) is fused at the N-terminus to a His-tag.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable