SAB5703037

Anti-Phospho-BRD4(pSer1083) Antibody, clone 5B6X4, Rabbit Monoclonal

• Synonyme(s) : BRD4, CAP, HUNK1, HUNKI, MCAP, bromodomain containing 4
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.46

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Matériaux: colorless
• Clone: 5B6X4, monoclonal
• Forme: liquid
• Poids mol.: 200 kDa
• Espèces réactives: human
• Concentration: 1mg/mL
• Technique(s): western blot: 1:100 - 1:500
• Couleur: colorless
• Isotype: IgG
• Séquence immunogène: HQSPP
• Numéro d'accès UniProt: O60885
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... BRD4(23476)

Description

Description générale

The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.

Immunogène

A synthetic phosphorylated peptide around S1083 of human BRD4 (NP_490597.1).

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Informations sur la sécurité

• Pictogrammes: GHS07,GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H317,H411
• Conseils de prudence: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Classification des risques: Aquatic Chronic 2 - Skin Sens. 1
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3