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Merck
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L8662

Sigma-Aldrich

L-Lysine monohydrochloride

98.5-101.0%, suitable for cell culture, non-animal source, meets EP, JP, USP testing specifications

Synonyme(s) :

(S)-2,6-Diaminohexanoic acid monohydrochloride

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About This Item

Formule linéaire :
H2N(CH2)4CH(NH2)CO2H·HCl
Numéro CAS:
657-27-2
Poids moléculaire :
182.65
Numéro Beilstein :
3563889
Numéro CE :
211-519-9
Numéro MDL:
MFCD00064564
Code UNSPSC :
12352209
ID de substance PubChem :
24896502
Nomenclature NACRES :
NA.26

product name

L-Lysine monohydrochloride, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Source biologique

non-animal source

Agence

meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

Pureté

98.5-101.0%

Forme

powder

Qualité

meets EP, JP, USP testing specifications

Technique(s)

cell culture | mammalian: suitable

Impuretés

endotoxin, tested

Couleur

white

Pf

263 °C (dec.) (lit.)

Solubilité

H2O: 100 mg/mL

Application(s)

pharmaceutical (small molecule)

Chaîne SMILES 

OC([C@@H](N)CCCCN)=O.[H]Cl

InChI

1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1

Clé InChI

BVHLGVCQOALMSV-JEDNCBNOSA-N

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Application


  • Scientific opinion on the presence of DNA in the feed additives consisting of concentrated liquid l-lysine, l-lysine monohydrochloride and concentrated liquid l-lysine monohydrochloride produced by Escherichia coliNITE BP-02917 for all animal species (METEX NOOVISTAGO).: This study explores the presence of DNA in l-lysine monohydrochloride and its variants used in animal feed, addressing safety concerns associated with genetic material in feed products (EFSA Panel et al., 2023).

  • Safety and efficacy of a feed additive consisting of concentrated liquid l-lysine, l-lysine monohydrochloride and concentrated liquid l-lysine monohydrochloride produced by Escherichia coliNITE BP-02917 for all animal species (Metex NoovistaGo).: Evaluates the safety and efficacy of l-lysine monohydrochloride in animal feed, contributing to a better understanding of its use and regulatory compliance (EFSA Panel et al., 2022).

  • Safety and efficacy of a feed additive consisting of l-lysine monohydrochloride and l-lysine sulfate produced by fermentation with Corynebacterium glutamicumCGMCC 17927 for all animal species (Barentz Animal Nutrition B.V.).: This publication assesses the safety and effectiveness of l-lysine monohydrochloride and l-lysine sulfate in various animal feeds, ensuring they meet health and nutritional standards (EFSA Panel et al., 2022).

  • Safety and efficacy of a feed additive consisting of l-lysine monohydrochloride and l-lysine sulfate produced by Corynebacterium glutamicum CGMCC 14498 for all animal species (Kempex Holland BV).: Investigates the implications of using l-lysine monohydrochloride and l-lysine sulfate in feed, focusing on their impact on animal health and growth (EFSA Panel et al., 2021).

  • Safety and efficacy of the feed additives concentrated liquid l-lysine (base) and l-lysine monohydrochloride produced by Corynebacterium glutamicum KCCM 80183 for all animal species (CJ Europe GmbH).: Analyzes the safety and benefits of concentrated liquid l-lysine and l-lysine monohydrochloride, detailing their advantages and regulatory approval for use in feed (EFSA Panel et al., 2021).


Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Guntur Fibriansah et al.
Nature communications, 6, 6341-6341 (2015-02-24)
Dengue virus (DENV) infects ~400 million people annually. There is no licensed vaccine or therapeutic drug. Only a small fraction of the total DENV-specific antibodies in a naturally occurring dengue infection consists of highly neutralizing antibodies. Here we show that
Lunzhi Dai et al.
Nature chemical biology, 10(5), 365-370 (2014-04-01)
We report the identification of a new type of histone mark, lysine 2-hydroxyisobutyrylation (Khib), and identify the mark at 63 human and mouse histone Khib sites, including 27 unique lysine sites that are not known to be modified by lysine
Przemyslaw Nogly et al.
IUCrJ, 2(Pt 2), 168-176 (2015-04-14)
Lipidic cubic phases (LCPs) have emerged as successful matrixes for the crystallization of membrane proteins. Moreover, the viscous LCP also provides a highly effective delivery medium for serial femtosecond crystallography (SFX) at X-ray free-electron lasers (XFELs). Here, the adaptation of
Chunaram Choudhary et al.
Nature reviews. Molecular cell biology, 15(8), 536-550 (2014-07-24)
Lysine acetylation is a conserved protein post-translational modification that links acetyl-coenzyme A metabolism and cellular signalling. Recent advances in the identification and quantification of lysine acetylation by mass spectrometry have increased our understanding of lysine acetylation, implicating it in many
Christian Schmidl et al.
Blood, 123(17), e68-e78 (2014-03-29)
CD4(+)CD25(+)FOXP3(+) human regulatory T cells (Tregs) are essential for self-tolerance and immune homeostasis. Here, we describe the promoterome of CD4(+)CD25(high)CD45RA(+) naïve and CD4(+)CD25(high)CD45RA(-) memory Tregs and their CD25(-) conventional T-cell (Tconv) counterparts both before and after in vitro expansion by
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