MABC140

Anti-ARC Antibody, clone 6F9.1

clone 6F9.1, from mouse

• Synonyme(s) : Activity-regulated cytoskeleton-associated protein, ARC/ARG3.1, Activity-regulated gene 3.1 protein homolog, Arg3.1
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 100
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: 6F9.1, monoclonal
• Espèces réactives: human
• Technique(s): immunohistochemistry: suitable (paraffin); western blot: suitable
• Isotype: IgG1κ
• Numéro d'accès NCBI: NP_056008
• Numéro d'accès UniProt: Q7LC44
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... ARC(23237)

Description

Description générale

Activity-regulated cytoskeleton-associated protein (ARC), also known as Activity-regulated gene 3.1 protein homolog (ARG3.1), plays an important role in synaptic plasticity and the formation of long-term memory. ARC is enriched in the postsynaptic density of dendritic spines and regulates endocytosis of AMPA receptors in response to synaptic activity and is required for homeostatic synaptic scaling of AMPA receptors. ARC also plays a role in the regulation of cell morphology, cytoskeletal organization, stress fiber dynamics, and cell migration.

Immunogène

GST-tagged recombinant protein corresponding to human ARC.

Application

Anti-ARC Antibody, clone 6F9.1 is a highly specific mouse monoclonal antibody, that targets ARC & has been tested in western blotting & IHC (Paraffin).

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected ARC in human brain tissue.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Qualité

Evaluated by Western Blotting in human hippocampus tissue lysate.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected ARC in 200 µg of human hippocampus tissue lysate.

Description de la cible

~ 45 kDa observed

Forme physique

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
Human hippocampus tissue lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable