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928097

Sigma-Aldrich

Gold nanoparticles

20 nm diameter, alkyne functionalized, 1 ML, OD 50, in water

Synonyme(s) :

AuNP, GdNP, Gold NP

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About This Item

Code UNSPSC :
12141717
Nomenclature NACRES :
NA.22

Niveau de qualité

100

Description

Alkyne surface density: 1/nm2

Concentration

in water

DO

50

Diam. du cœur

20 nm , coefficient of variance <12%

Diamètre

20 nm

λmax

524 nm

PDI

<0.200

Groupe fonctionnel

alkyne

InChI

1S/Au

Clé InChI

PCHJSUWPFVWCPO-UHFFFAOYSA-N

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Description générale

Alkyne functionalized gold nanoparticles are suitable for covalent conjugation of any azide-tagged molecule through Cu(I)-catalyzed click chemistry. These gold nanoparticles allow for rapid generation of gold conjugates for subsequent use in downstream assays.
Alkyne functionalized gold nanoparticles are more than 95% spherical and have uniform size distribution (CV <12%).

Application

Ideal for development of gold conjugates for use in applications such as blotting, lateral flow assays, microscopy, and transmission electron microscopy (TEM).

Stockage et stabilité

When stored for a long period of time gold nanoparticles may sediment at the bottom of the vial, which is especially prominent for larger particle sizes. Prior to use, re-suspend the sedimented particles by thorough mixing until a homogenous solution is obtained.

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

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Consulter la Bibliothèque de documents

Gold nanoparticles: synthesis and applications in drug delivery.
Khan A K, et al.
Tropical Journal of Pharmaceutical Research, 1169-1177 (2014)
Wilson Luo et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 23(5), 1052-1059 (2016-10-12)
In this study, we report the design, synthesis, and characterization of small 3 nm water soluble gold nanoparticles (AuNPs) that feature cyclopropenone-masked strained alkyne moieties capable of undergoing interfacial strain-promoted cycloaddition (i-SPAAC) with azides after exposure to UV-A light. A strained
Mingmin Li et al.
Nanotheranostics, 3(1), 113-119 (2019-03-23)
Surface-enhanced Raman spectroscopy (SERS) has proven a powerful tool for multiplex detection and imaging due to its narrow peak width and high sensitivity. However, conventional SERS reporters are limited to thiolated compounds, which have limitations such as chemical stability and

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