803987

N-(4-(benzyloxy)-2-methylbutan-2-yl)-2-chloroaniline

• Formule empirique (notation de Hill): C₁₈H₂₂ClNO
• Poids moléculaire : 303.83
• Code UNSPSC : 12352100
• ID de substance PubChem : 329768838
• Nomenclature NACRES : NA.22

Propriétés

• Forme: liquid
• Température de stockage: 2-8°C
• Chaîne SMILES: CC(CCOCC1=CC=CC=C1)(C)NC2=C(Cl)C=CC=C2
• InChI: 1S/C18H22ClNO/c1-18(2,20-17-11-7-6-10-16(17)19)12-13-21-14-15-8-4-3-5-9-15/h3-11,20H,12-14H2,1-2H3
• Clé InChI: KEXYAYZJBMLTHS-UHFFFAOYSA-N

Description

Application

Traditionally challenging to access, this hindered amine provides a chemically differentiated building block for organic synthesis and medicinal chemistry, specifically for preparation of drug candidates containing hindered amine motifs. Additionally, this and over 80 other sterically hindered secondary amines in the Sigma-Aldrich portfolio provide structurally distinct screening compounds. Screen several through Aldrich Market Select. This hindered amine was accessed via a recent publication reported by Baran and coworkers using an innovative hydroamination method.

Autres remarques

Practical olefin hydroamination with nitroarenes

Informations sur la sécurité

• Pictogrammes: GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H410
• Conseils de prudence: P273 - P391 - P501
• Classification des risques: Aquatic Acute 1 - Aquatic Chronic 1
• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable