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Merck

TLR7

toll-like receptor 7

Synonymes:
TLR7-like
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(51284) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]
  • Mouse(170743) toll-like receptor 7
  • Rat(317468) toll-like receptor 7
  • naked mole-rat(101705918) toll-like receptor 7
  • domestic guinea pig(100713329) toll-like receptor 7
  • cow(493686) toll-like receptor 7
  • Horse(791248) toll-like receptor 7
  • sheep(554254) toll-like receptor 7
  • Goat(100860934) toll-like receptor 7
  • dog(491743) toll-like receptor 7
  • Zebrafish(100534776) toll-like receptor 7
  • chicken(418638) toll-like receptor 7
  • domestic cat(493685) toll-like receptor 7

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
Imiquimod, ≥98% (HPLC), solid,
Espèce(s)
human
Imiquimod, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human

Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
Hydroxychloroquine sulfate, ≥98% (HPLC), powder,
Espèce(s)
human
Hydroxychloroquine sulfate, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Hydroxychloroquine Sulfate, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
Hydroxychloroquine sulfate, analytical standard,
Espèce(s)
human
2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol, British Pharmacopoeia (BP) Reference Standard,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-TLR7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-TLR7 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse
Application
ELISA
immunocytochemistry

western blot
Monoclonal Anti-TLR7 antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
Monoclonal Anti-TLR7 antibody produced in mouse, clone 2F8, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
Anti-TLR7 Mouse mAb (2C9), liquid, clone 2C9, Calbiochem®,
Espèces réactives
human
Application

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Tlr7,
Espèce(s)
mouse
MISSION® esiRNA, targeting human TLR7,
Espèce(s)
human