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Merck

TLR4

toll-like receptor 4

Synonymes:
ARMD10, CD284, TLR-4, TOLL
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(7099) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(21898) toll-like receptor 4
  • Rat(29260) toll-like receptor 4
  • naked mole-rat(101715916) toll-like receptor 4
  • dog(403417) toll-like receptor 4
  • cow(281536) toll-like receptor 4
  • Horse(100066890) toll-like receptor 4
  • Domestic Rabbit(100009497) toll-like receptor 4
  • sheep(554263) toll-like receptor 4
  • Goat(100860955) toll-like receptor 4
  • domestic guinea pig(100724803) toll-like receptor 4
  • domestic cat(493698) toll-like receptor 4
  • chicken(417241) toll-like receptor 4

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ELISA

Référence du produit
Description
Espèce(s)
Human TLR-4 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-TLR4 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-TLR4 antibody produced in mouse, clone 3B6, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunohistochemistry

western blot
Anti-TLR4 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-TLR4 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
Anti-TLR4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human TLR4,
Espèce(s)
human