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Merck

TIMP1

TIMP metallopeptidase inhibitor 1

Synonymes:
CLGI, EPA, EPO, HCI, TIMP
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(7076) Summary: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]
  • Mouse(21857) tissue inhibitor of metalloproteinase 1
  • Rat(116510) TIMP metallopeptidase inhibitor 1
  • domestic cat(101095886) TIMP metallopeptidase inhibitor 1
  • naked mole-rat(101722238) TIMP metallopeptidase inhibitor 1
  • dog(403816) TIMP metallopeptidase inhibitor 1
  • cow(282092) TIMP metallopeptidase inhibitor 1
  • domestic guinea pig(101787552) TIMP metallopeptidase inhibitor 1
  • sheep(443331) TIMP metallopeptidase inhibitor 1
  • Horse(100034220) TIMP metallopeptidase inhibitor 1

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ELISA

Référence du produit
Description
Espèce(s)
Human TIMP-1 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human
Rat TIMP-1 ELISA Kit, for cell and tissue lysates,
Espèce(s)
rat
Human TIMP-1 ELISA Kit, for cell and tissue lysates,
Espèce(s)
human
Mouse TIMP-1 ELISA Kit, for cell and tissue lysates,
Espèce(s)
mouse
Mouse TIMP-1 ELISA Kit, for serum, plasma and cell culture supernatant,
Espèce(s)
mouse

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-TIMP-1 Antibody, clone 1H19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
affinity binding assay
immunohistochemistry

western blot
Anti-TIMP-1 Antibody, Chemicon®, from rabbit,
Espèces réactives
bovine, ferret, horse, rabbit, rat, sheep
Application
ELISA
immunohistochemistry

western blot
Anti-TIMP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Monoclonal Anti-TIMP1 antibody produced in mouse, clone 4D12, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunoprecipitation (IP)

western blot
Anti-TIMP1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot

Proteins

Référence du produit
Description
Espèce(s)
TIMP-1 human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Espèce(s)
human
TIMP1 human, recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE),
Espèce(s)
human
TIMP-1, recombinant, active human, ,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Timp1,
Espèce(s)
mouse
MISSION® esiRNA, targeting human TIMP1,
Espèce(s)
human