Accéder au contenu
Merck

STRADB

STE20-related kinase adaptor beta

Synonymes:
ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(55437) Summary: This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
  • Mouse(227154) STE20-related kinase adaptor beta
  • Rat(501146) STE20-related kinase adaptor beta
  • domestic guinea pig(100712796) STE20-related kinase adaptor beta
  • cow(506029) STE20-related kinase adaptor beta
  • sheep(101108549) STE20-related kinase adaptor beta
  • dog(478870) STE20-related kinase adaptor beta
  • Goat(100861151) STE20-related kinase adaptor beta
  • Domestic Rabbit(100342882) STE20-related kinase adaptor beta
  • naked mole-rat(101700434) STE20-related kinase adaptor beta
  • domestic cat(101094615) STE20-related kinase adaptor beta
  • Horse(100066574) STE20-related kinase adaptor beta
  • chicken(424083) STE20-related kinase adaptor beta

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-STRADB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot
Anti-ILPIP antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
ANTI-MOUSE STRADB (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
mouse
Application
western blot
Anti-STRADB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Stradb,
Espèce(s)
mouse
MISSION® esiRNA, targeting human STRADB,
Espèce(s)
human