SSX4
synovial sarcoma, X breakpoint 4
Synonymes:
CT5.4
Espèce(s):
ID UniProtKB:
ID du gène:
- Human(6759) Summary: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-SSX4 antibody produced in mouse, clone 3E10, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-SSX4, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry