Accéder au contenu
Merck

SRD5A2

steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)

Synonymes:
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6716) Summary: This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008]
  • Mouse(94224) steroid 5 alpha-reductase 2
  • Rat(64677) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
  • sheep(100820756) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
  • chicken(772291) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
  • naked mole-rat(101708836) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
  • domestic cat(101086898) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
  • dog(403715) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
  • domestic guinea pig(100731664) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
  • cow(527024) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-SRD5A2, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, horse, human
Application
western blot
Anti-SRD5A2 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
canine, human, rat
Application
ELISA
western blot
Monoclonal Anti-SRD5A2 antibody produced in mouse, clone 1F4, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
Anti-SRD5A2 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
Finasteride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Finasteride, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
Finasteride for peak identification, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
Finasteride, British Pharmacopoeia (BP) Reference Standard,
Espèce(s)
human
Dutasteride, ≥98% (HPLC),
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human SRD5A2,
Espèce(s)
human