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Merck

RGS4

regulator of G-protein signaling 4

Synonymes:
RGP4, SCZD9
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5999) Summary: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(19736) regulator of G-protein signaling 4
  • Rat(29480) regulator of G-protein signaling 4
  • domestic guinea pig(100717645) regulator of G-protein signaling 4
  • naked mole-rat(101713440) regulator of G-protein signaling 4
  • domestic cat(101083058) regulator of G-protein signaling 4
  • chicken(378901) regulator of G-protein signaling 4
  • sheep(100381246) regulator of G-protein signaling 4
  • cow(617437) regulator of G-protein signaling 4
  • dog(488666) regulator of G-protein signaling 4
  • Zebrafish(569876) regulator of G-protein signalling 4
  • Domestic Rabbit(100009014) regulator of G-protein signaling 4

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-RGS4 Antibody, serum, from rabbit,
Espèces réactives
rat
Application
western blot
Monoclonal Anti-RGS4 antibody produced in mouse, clone 2B2, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
Anti-RGS4 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Rgs4,
Espèce(s)
mouse