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Merck

RASGRP2

RAS guanyl releasing protein 2 (calcium and DAG-regulated)

Synonymes:
CALDAG-GEFI, CDC25L
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(10235) Summary: The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(19395) RAS, guanyl releasing protein 2
  • Rat(361714) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • sheep(101104023) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • dog(612101) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • domestic cat(101094450) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • Horse(100055959) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • Zebrafish(557063) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • naked mole-rat(101714183) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • domestic guinea pig(100722152) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • Domestic Rabbit(100328903) RAS guanyl releasing protein 2 (calcium and DAG-regulated)
  • cow(512056) RAS guanyl releasing protein 2 (calcium and DAG-regulated)

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-phospho RasGRP2 (Ser554), from rabbit,
Espèces réactives
baboon, human, monkey, mouse, porcine, rabbit, rat
Application
western blot
Anti-RASGRP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-phospho RasGRP2 (Ser586), from rabbit,
Espèces réactives
monkey, mouse, rat
Application
western blot
Anti-RASGRP2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-phospho RasGRP2 (Ser116/Ser117), from rabbit,
Espèces réactives
monkey, mouse, rat
Application
immunofluorescence
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Rasgrp2,
Espèce(s)
mouse
MISSION® esiRNA, targeting human RASGRP2,
Espèce(s)
human